Despite sharing the same Neopolitan origins, Ziti alla Genovese and Spaghetti alle Vongole are quite different. First of all, they have differnt types of noodles, with Ziti alla Genovese being made with a long, hollowed-out pasta shape. It is also made with a different type of meat. Instead of seafood, Ziti alla Genovese is made with a beef and onion sauce. It is the perfect dish for a traditional Italian sunday lunch.